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A Little Known Nutrient That Can Heal Your Gut And Blast Your Immunity Through The Roof.

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It was way back in 2009 that I first discovered goat’s milk.

I had just finished interviewing Joe Stout – a food scientist at a small local goat farm called “Mt. Capra”. During our podcast (which you can listen to here), Joe filled me on some very interesting properties of goat’s milk that make it much, much different than cow’s milk, including…

…the difference in allergic reactions between goat’s milk and cow’s milk, and why the difference exists…

….what happens to cow’s milk during homogenization that makes it especially dangerous for athletes and people worried about cancer…

…why the body absorbs goat’s milk protein at a much, much faster rate than cow’s milk protein…

…how cow’s milk can cause lactose intolerance, and why this rarely happens with goat’s milk…

…and why goat’s milk “matches up” to the human body better than cow’s milk.

Over at Mark’s Daily Apple  just last week, this was recently confirmed, in an article that says:

“Lots of people seem to fare better with goat milk than cow milk, and several studies support these anecdotes:

-Goat milk is both anti-allergenic and anti-inflammatory, regulating the intestinal immune response at the cellular level.

-Goat milk possesses immunomodulatory effects and even helps the body release nitric oxide, a vasodilator that improves vascular function.

-Goat milk glycans (carbohydrates that support the healthy gut bacteria and can help the immune system) are more similar to human milk glycans than cow milk glycans; goat milk also contains novel glycans with further health benefits.”

Anyways, after that original podcast with Joe, I asked him what to do if I wanted to get all the beneficial properties of goat’s milk (and as I later discovered) much more, without actually drinking milk every day, because frankly, I’m just not a milk-guzzling kind of guy.

Joe’s response changed my life, and you’re about to discover why.

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What Is Colostrum?

Joe told me, “Simple. Colostrum.”

At this point, colostrum was kind of woo-woo for me. My wife grew up on a sheep farm so I knew colostrum had something to do with sheep’s milk, but wasn’t really sure what it really, truly was.

Joe explained to me that colostrum is produced by not just goats and sheep, but by all mammals (including humans) in the first few days after giving birth. Also known as “first milk”, it is produced in the mammary glands of females just prior to giving birth, and serves as a concentrated source of proteins, growth factors, and antibodies that are essential for early development of newborns.

Its properties have been revered for thousands of years across many cultures: in ancient Chinese medicine it was regarded as a potent health tonic, and for the Maasai people of Kenya and Tanzania it has long been regarded as a crucial part of a warrior’s diet. In Britain, dairy farmers refer to colostrum as beestings, and they used any surplus colostrum to make an extra-creamy, and very healthy, pudding.

So you can literally think of colostrum as a powerhouse of nutritional ammunition designed to get a newborn through the critical first few days of life.

Now let’s move on to a slightly more scientific definition of colostrum for you nerds out there, straight from the underbellies of the Wiki definition of colostrum:

“Newborns have very immature digestive systems, and colostrum delivers its nutrients in a very concentrated low-volume form. It has a mild laxative effect, encouraging the passing of the baby’s first stool, which is called meconium. This clears excess bilirubin, a waste-product of dead red blood cells, which is produced in large quantities at birth due to blood volume reduction, from the infant’s body and helps prevent jaundice. Colostrum is known to contain immune cells (as lymphocytes)[4] and many antibodies such as IgA, IgG, and IgM. These are the major components of the adaptive immune system. Inter alia IgA is absorbed through the intestinal epithelium, travels through the blood, and is secreted onto other Type 1 mucosal surfaces[citation needed]. Other immune components of colostrum include the major components of the innate immune system, such as lactoferrin,[5] lysozyme,[6] lactoperoxidase,[7] complement,[8] and proline-rich polypeptides (PRP).[9] A number of cytokines (small messenger peptides that control the functioning of the immune system) are found in colostrum as well,[10] including interleukins,[10] tumor necrosis factor,[11] chemokines,[12] and others. Colostrum also contains a number of growth factors, such as insulin-like growth factors I (IGF-1),[13] and II,[14] transforming growth factors alpha,[15] beta 1 and beta 2,[16][17] fibroblast growth factors,[18] epidermal growth factor,[19] granulocyte-macrophage-stimulating growth factor,[20] platelet-derived growth factor,[20] vascular endothelial growth factor,[21] and colony-stimulating factor-1.[22]

Colostrum is very rich in proteins, vitamin A, and sodium chloride, but contains lower amounts of carbohydrates, lipids, and potassium than mature milk. The most pertinent bioactive components in colostrum are growth factors and antimicrobial factors. The antibodies in colostrum provide passive immunity, while growth factors stimulate the development of the gut. They are passed to the neonate and provide the first protection against pathogens.”

Whew. I know that was a propellor-hat friendly mouthful, so let’s dig into the more practical aspects of how you can use colostrum if you happen to be one of my readers that is not a newborn or 2 day old mammal.

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Colostrum As An Alternative To Antibiotics

The immunoglobulins in colostrum have specific immune system activity against many common human pathogens such as Escherichia coli, Cryptosporidium parvum, Shigella flexneri, Salmonella, Staphylococcus, and rotavirus (yes, that nasty diarrhea disease).

Interestingly, prior to the development of antibiotics, colostrum was the primary source of immunoglobulins used to fight infections. When Albert Sabin made his first oral vaccine against polio, the immunoglobulin he used actually came from colostrum. When antibiotics began to appear, interest in colostrum waned, but, now that antibiotic-resistant strains of pathogens have developed, interest is once again returning to natural alternatives to antibiotics like colostrum.

I personally don’t take colostrum year-round (later in this article I’ll tell you why I don’t take colostrum all the time), but prior to travel or during cold and flu season I “load” with colostrum for several weeks.

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Colostrum For Immunity

Perhaps you have heard of “Proline-Rich Polypeptides” or PRP. These things have been making the news all over scholarly medical research articles lately due to their huge potential for boosting the immune system. So in addition to the infection-fighting immunoglobulins you’ve already learned about, these PRP’s offer a second level of protection.

PRP’s are tiny immune signaling peptides that have been discovered in colostrum (and also in other sources, such as blood plasma). Also known as “Colostrinin”, “CLN”, and “transfer factor”, they function as signal transducing molecules that have the unique effect of making microadjustments to your immune system, turning your immunity up when the body comes under attack from pathogens or other disease agents, and damping your immune system down when the danger is eliminated or neutralized. This is called cell-mediated immunity, and is basically a process of keeping your immune system finely tuned.

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Colostrum For Enhancing The Effectiveness of Probiotics

Because colostrum helps to heal leaky gut and make the tight junctions in your gut less permeable to foreign invaders, without colostrum, probiotics will not be as effective long term because they will pass through your GI tract and not “stick around” in your gut the way they are supposed to. In this way, clostrum is like soil for the seeds of probiotics. It gives friendly bacteria a place to grow by keeping leaky junctions in your gut more “closed”. This has to do with a protein called Zonulin.

In his recent Digestion Session Summit, Sean Croxton interviewed Dr. Datis Kharrazian and in the transcript of the interview, Dr. Kharrazian explained it this way:

what is zonulin

So basically, colostrum keeps zonulin protein from opening up your intestinal cells and keeps leaky gut from developing. Hence, your probiotics become more effective.

In addition, since colostrum also contains a large concentration of immune system factors like white blood cells (leukocytes) and antibodies, the combination of probiotics and colostrum together boost your immune system tremendously.

In addition, if you are trying to re-colonize your GI tract (raise the levels of friendly bacteria in your gut) then you should also combine colostrum with probiotics. When you have a healthy population of friendly bacteria combined with colostrum for the probiotics to cultivate, a more hostile environment is created for harmful microorganisms and there is less space for digestion disruptors to proliferate. So colostrum combined with probiotics is a very powerful one-two gut-healing combo for gas, bloasting, diarrhea, constipation.

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Colostrum For Athletic Performance

For me, athletic performance enhancement and the prevention of gas, nausea, cramps or diarrhea during hard workouts and races was a big reason to begin using colostrum, and I particularly achieve this by “loading” with 8 colostrum capsules per day for 2 weeks before hard races – especially races in hot conditions, such as Ironman Hawaii.

A gastroenterologist professor named Raymond Playford, of Plymouth University, has done some very interesting research on the gut benefits of colostrum for athletes, and has published one study entitled: “The nutriceutical, bovine colostrum, truncates the increase in gut permeability caused by heavy exercise in athletes.

When we are in intense periods of training, us athletes and exercise enthusiasts (you know who you are) often develop gut problems, also known as  “runners’ trots”. If you’ve ever had to pull over on the side of the road during a run with your head between your knees because of gastric distress, or you’ve ever had to interrupt a set in the weight room to quickly duck into the locker room, then you know what I mean.

In the video below, Dr. Playford explains how this is caused by a combination of stress and the simultaneous raising of your body’s core temperature by about two degrees, which increases the permeability of your gut wall, allows toxins into the bloodstream that wouldn’t normally be there, and is the primary reason you get gut distress during stressful exercise, especially stressful exercise in the heat. This is because heat raises the permeability of your gut wall even more.

In this video, Dr. Playfored also talks about his fascinating research on colostrum, its role in protecting this gut leakage that happens during strenuous exercise, and the fact that if you take colostrum for two weeks prior to exercise, the change in gut leakiness is almost completely prevented.

This all makes sense, since colostrum contains growth factors designed to strengthen the gut lining, which is crucial for a newborn mammal, who has a very permeable gut that needs to toughen up fast (and this is why babies or children raised on soy milk – or anyone who has ever been on a bout of gut disrupting antibiotics – should undoubtedly be considering colostrum).

Of course, it’s not just gut problems that colostrum helps to address in athletes. Other studies show that athletes who take it are as much as 20% less likely to get infections of the upper respiratory tract, for reasons you’ve already learned.fs

In this article from the Guardian, Playford expounds on the other benefits that active people can derive from colostrum, “It could be really useful to people who have to do physical exercise in hot conditions, such as soldiers in Afghanistan,” he says. “They are susceptible to heatstroke because of all the gear they have to wear and carry, and taking colostrum could reduce that very serious risk. Another group who could benefit are older people with arthritis who develop serious gut problems because of the strong painkillers they use, and those with ulcerative colitis. These patients are at risk of damage to their gut lining and the colostrum helps it to heal and reduces its permeability.”

As a final boost for athletes, colostrum also has antioxidant components, such as lactoferrin, which assists with iron absorption, bone density and has been shown to have anti-microbial characteristics and hemopexin, which scavenges the heme released or lost by the turnover of heme proteins such as hemoglobin and thus protects the body from the oxidative damage that free heme can cause. This is especially important for endurance athletes, who have high hemoglobin use and red blood cell turnover.

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Colostrum For Growth Hormone (And A Strict Warning!)

Finally colostrum also contains Insulin Like Growth Factor-1 (IGF-1). Low IGF-1 levels are not only associated with dementia in the elderly, but people with eating disorders also have low levels of IGF-1 due to malnutrition, as do obese individuals.

The growth-promoting effects most people associate with growth hormone are actually caused by IGF-1, which has characteristics of both growth hormone and growth factor since it stimulates the growth, proliferation, and survival of cells such as gut tissue cells and muscle tissue cells. This is why both IGF-1 and growth hormone are often promoted for muscle building, anabolism, recovery and anti-aging.

IGF-1 also acts as a neurotrophic factor in the brain, which means that it contributes to neurogenesis (growth of new brain cells) and survival of existing neurons (known as a neuroprotective effect).

Now here’s the important part: overexpression of growth hormone by 100 to 1,000-fold in mice causes a 50% shorter lifespan, mainly due to kidney and liver dysfunction. In addition, since IGF-1 and growth hormone are “pro-growth”, excessive long-term use could eventually cause some pretty rapid cell division – which is also known as…cancer.

Author Tim Ferriss calls this a trade-off or a “faustian bargain” between longevity and performance, and you can learn more about it in this excellent WellnessFX article by Dr. Rhonda Patrick entitled “The IGF-1 Trade-Off: Performance vs. Longevity”.

So for the same reason I don’t guzzle a gallon milk a day, eat grass-fed steak for breakfast, lunch and dinner, or take massive doses of whey protein after a workout, I don’t “overuse” colostrum. I simply load with colostrum for 2 weeks prior to big workouts and races, take it when I know I’ve been exposed to the cold or flu, and then also take it (as 4 capsules in the morning and 4 capsules in the evening) during most of the winter (about November through February) when I know my immune system is more likely to become compromised.

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Summary

Of course, as I alluded to at the beginning of this post, if you’re going to use colostrum as an alternative to antibiotics, as a boost for your immune system, as a way to make your gut feel bulletproof during exercise, to enhance the effectiveness of probiotics, or as a method for increasing growth hormone and iron absorption, then I highly recommend that you use the most biocompatible form of colostrum you can get.

You guessed it: you should get your colostrum from goats.

Because of this, I’ve just put the finishing touches on designing NatureColostrum, which is human gut-friendly goat’s colostrum harvested from organic, pastured goats straight from Joe’s farm, just a few hours from my house. You can click here to grab it now.

This is literally the most biocompatible colostrum on the face of the planet, and is of course from grass-fed, free-range goats that graze on pesticide-free and chemical-free pasture 365 days a year. No pesticides, no antibiotics and no hormones are used. Ever.

Enjoy your discovery of this little known compound, and leave your questions, comments or feedback below!

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38 thoughts on “A Little Known Nutrient That Can Heal Your Gut And Blast Your Immunity Through The Roof.

  1. Is colostrum ok for someone with SIBO?

    I’m learning that with SIBO, a lot of” “good” things are actually not so good for you. Like fermented foods…

    1. With SIBO one of the toughest factors to overcome is the biofilm buildup that is common to the overgrowth. Lactoferrin really attacks biofilms with a vengeance and therefore I would think a colostrum supplement would be extremely beneficial. I really can’t see any reason why colostrum would be contraindicated for SIBO.

  2. Very interesting! If colostrum boosts your immune system, how might it affect someone with an autoimmune disorder (ex: alopecia). Could it potentially accelerate the autoimmune disorder to a worsened state, or is it more likely to balance the immune system and restore it to normal function?

  3. Ben,

    What do you think of using colostrum if a Metametrix GI Effects test says you have a low grade fungal infection? Would colostrum be better than fermented foods in that case?

  4. Hi Ben,

    Great read as always.

    However I have contacted supplier that I’ve been using colostrum from, on cancer state in a body issue, their reply was:

    “From what we understand, all the studies (that we have seen) that make claims to the effect of IGF-1 and growth hormone creating a cancer state in the body, were using synthetic forms of the compound to isolate it for research. This very well could cause cell division to happen in that way in it’s synthetic form.

    In a whole food form, we understand that all the co-factors and nutrients help the body to metabolize the growth factors appropriately. Couple that with the fact that our hormones and cell division naturally decline with age, there should be no need to worry about growth factors when they are derived from natural whole food sources.”

    Be interesting to hear your take on that.

    Regards,

    Egis

    1. I should begin by clarifying the fact that I am *not* a physician and this is *not* to be interpreted as medical advice. Please talk to a licensed medical professional about all of this!

      The 1985 Steven Rosenberg book, Quiet Strides in the War on Cancer, first popularized the benefits of cytokines in the treatment of cancer. Since that time, the same cytokines found in colostrum (interleukins 1, 6, 10, interferon G, and lymphokines) have been the single most researched protocols in scientific research for the cure for cancer.

      Colostrum lactalbumin has been found to be able to cause the selective death (apoptosis) of cancer cells, leaving the surrounding ¯noncancerous tissues unaffected. Lactoferrin has similarly been reported to possess anti-cancer activity.

      So the mix of immune and growth factors in colostrum may inhibit the spread of cancer cells.

  5. I’ve been diagnosed with leaky gut and looking for a cure, so happy to hear about this. One problem, according to my blood test, I’m allergic to goats milk (and anything that even looks like dairy). I wonder if taking colostrum in pill form, do you think I’d have a reaction to it?

    Thanks Ben!

  6. I’m trying to find a little more information about this product – is it prepared with low heat? Are there any other ingredients besides colostrum? How is this different than Capra’s goat colostrum? Is it possible to get a sample to make sure I can tolerate it? (I am allergic to dairy). Thanks!

  7. You mention that colostrum and probiotics should be combined. Do you mean that they should be taken simultaneously? Or is it just as effective to take colostrum 30 minutes before food and then my daily probiotic after my dinner meal? Thank you

  8. Hello Ben! I’ve been taing a strong antibiotic in December, clindamycin 600mg for teeth surgery and since than, I have a looot of digestive problems, I think my flora is damaged and I developed some food sesitivities, cold hands and feet after eating, bloating, a feeling that something isn’t ok in my gut, fatigue and so on. I was searching for different helpers and I found out about colostrum. What do you think? Should I give a try?

  9. In researching the benefits of goat colostrum, and the availability (or lack thereof) in Canada, apparently it is not to be produced in Canada by goat milk producers) I came to a couple of observations regarding colostrums benefits for Ulcerative Colitis and Chrone’s sufferers. The following is just a hunch, but it does seem to connect some possible dots.

    Since colostrum acts as an epigenetic switch to turn-on the digestive tract cells in newborns, the same may be the case for regenerated digestive cells of those suffering from IBD problems. Follow me hear for a moment.

    One of the frustrating and debilitating problems faced periodically by UC and Chrone’s sufferers is the increasingly cyclical nature of the disease process. It occurred to me there may be a reason for this cycle. When the cells lining the digestive tract regenerate, healing seems to occur, but somewhat momentarily, because several months later, the whole debilitating process will repeat itself, often becoming more severe each time around. The auto-immune response is being implicated in causing this cycle, but why? The auto-immune part is understood, but the “why” is not. When the digestive tract heals, new cells heal into the place of the ulcerations. The inflammatory symptoms disappear. But the new cells replacing the damage, although perfect cells, are not activated! The immune system, trying to protect the body which is its job, concludes these cells are not functioning as proper digestive tract cells, so it attacks, and the debilitating disease process begins all over again. This cycle becomes increasingly severe, because when the disease process is in acute phase, there is always inflammation as well as the ulceration, so the areas affected are replaced with increasing numbers of new cells during healing, each time with larger peripheral areas of damage being affected then healed, then again attacked. If the cells laid down during the healing phase are not activated to perform their job, the immune system will inevitably attack again. Thus the cycle effect. What is needed is the epigenetic switch to turn the new cells on, just the same as in a newborn. The cells are there, and they are healthy, and waiting to be switched on! If not switched on, the immune system will determine these cells are not acting normally, and attack! So, to maintain healing and to avoid the cycle effect, the identical cell activating epigenetic switch is needed! Colostrum!

    Some folk say colostrum does nothing for their problem. Likely that is because they either have not been able to obtain a viable colostrum, or they are taking it in an improper manner. Colostrum in the newborn is the very first thing that is introduced into an empty digestive tract before any other form of nourishment. Therefore colostrum should be ingested when the digestive system is basically at rest and empty of other foods. The idea is to feed the new digestive cells with the epigenetic switch so the cells are prepared to take up their roles. If this happens properly, the cells will be activated, and the immune system will not view the cells of new healing as rogue, so will not attack. The negative disease cycle is broken!

    We are looking for goat colostrum rather than bovine, because although most colostrum does not contain much actual milk, there may be a very slight milk componant. Our family member who has UC is allergic to the cassein in bovine milk. The bovine colostrum he has taken has helped with increased energy, but he is showing allergic symptoms (difficulty swallowing, wheezing with shortness of breath, and tightness in the chest.) Other family members with intolerance to bovine dairy have successfully consumed goat’s milk over the years without adverse reactions, so he wants to give the goat colostrum a try since he already knows colostrum is helping apart from the allergic symptoms. The goat cassein molecule is smaller and different than bovine.

    Anyway, thought I would pass along my thoughts and observations for what they may be worth.

  10. Hey Ben,

    Thanks for all your awesome work.

    In regards to the “Strict Warning” for overconsumption of Colostrum due to IGF1 increases. The article you linked to by Dr. Rhonda states… “Overexpressing growth hormone by 100 to 1,000-fold in mice causes a 50% shorter lifespan, mainly due to kidney and liver dysfunction.”

    I can’t believe taking a moderate amount of Colostrum daily would get my IGF1 to increase by 100 to 1000 times it’s current levels. Right?

    I started taking raw, 6 hour certified colostrum by Immune Tree 3 days ago and can absolutely tell a difference in my energy levels and workout performance. Honestly the best supplement I have taken….maybe ever.

    Just as a safe guard I am going to get my IGF1 levels tested and then test again after a couple months to see if there is any crazy increase due to daily colostrum intake.

  11. hello

    is Colostrum safe for 10 year olds with yeast and a leaky gut?

    how long should he be taking it? he is taking a probiotic, a L Glutamine and fish oils….along with a changed diet.

    1. Yes. Colostrum is in breastmilk, after all! Until the leaky gut is healed, he can take it. I should clarify the fact that I am *not* a physician and this is *not* to be interpreted as medical advice. Please talk to a licensed medical professional about all of this!

  12. I started recently taking colostrum from Sovereign Labs. For whatever reason, threw it in my bulletproof coffee getting a stable massive foam topper like never before. Sovereign says not to take it with any acidic beverages (coffee, o.j.) and their email said:* Taking Colostrum-LD with extra proteins will increase the digestion time to two hours. Please only mix with water, no acidic beverages either. Of course, you can do whatever you would like with your Colostrum-LD, but this is what we recommend. * Well there’s no protein in coffee . . . so why not mix colostrum with acidic beverages? At this point, my only goal is to take it on an empty stomach . . . many thanks

  13. Hi Ben,

    Can you take L-glutamine and Colostrum together on an empty stomach, or are they better taken apart from each other?

    Cheers

    Grant

  14. Ben, what do you think about taking this for adrenal fatigue/exhaustion? I was crashed, but have recovered a lot over the past 9 months. I’m not back to where I want to be yet though. I figured this could be a big plus over the winter to ward off illness and to help heal more rapidly.

    1. I am not a doctor and this is not to be taken, interpreted or construed as medical advice. Please talk with a licensed medical professional about this. These are just my own personal thoughts and not a prescription or a diagnosis or any form of health care whatsoever. But I've never seen any contraindications for these two…

    1. Yep, email [email protected]

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