Testosterone Replacement Therapy, Hormone Testing 101, Spot-Reducing Fat Loss Cream, The Benjamin Button Longevity Cocktail & Much More With Adam Lamb of RenewLifeRX.

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Testosterone Replacement Therapy
Hormones, Podcast

Adam Lamb is the founder and manager of RenewLifeRX, a hormone optimization clinic. He has spent the last 10 years helping to explore and facilitate the process of hormone optimization through strategies such as stem cells, peptides, testosterone replacement therapy, and others.

He is also the author of the best selling book “Better Than the Binge, Overcoming the Social Obligation of Alcohol” where he helps ordinary people remove alcohol from their life so they can accomplish extraordinary things.

Adam is a devoted husband of over 12 years and a father to an 11-year-old son and 7-year-old daughter. He often speaks on managing the daily challenges of being an entrepreneur, family man, and keeping himself in peak physical condition. If you asked him to “sum up” his lifestyle in one word, it would be “discipline.”

During this discussion, you'll discover:

-What effects a poor night of sleep or high alcohol consumption can have on your hormones…7:04

-How to gain a birds-eye view of your overall hormone quality…10:34

  • Understand the story of your life: environment, history, genetics, etc.
  • Phase 1 test: CBC, metabolic, lipid, DHEA, total testosterone, TSH, IGF-1, FSH, LH, PSA, SHBG, estradiol
    • CBC is for standard overall health
    • DHEA can be used to regulate circadian rhythm, overall health, rather than testosterone
    • Total testosterone
    • IGF-1 levels reveal sleep, stress, recovery; potential red flag for pituitary dysfunction
    • FSH, LH baseline, message from the brain to the testes
    • High PSA levels may be indicative of prostate problems
    • SHBG (sex hormone-binding globulin) levels rise on high fat, low carb diet
  • Thyroid medication is one of the most overused medications
  • Testosterone therapy is not intended to be a permanent solution
  • Lack of sleep, stress, etc. affect the brain's communication w/ the body regarding testosterone production
  • Many variables can affect estrogen levels, which makes it an unreliable indicator of hormone health
  • There are no absolutes; everyone's body absorbs, responds differently

-Why Adam only uses blood tests to quantify his patients' hormone quality…34:10

  • Trust factor: tried and true
  • Other tests such as the DUTCH test are sourced out when necessary
  • Every 6 months is the gold standard for the max time between tests
  • Longtime patients are self-experts
  • Potential to identify other health concerns when blood is tested regularly

-What variables are tested differently for women vs. men…41:20

  • Pregnenolone, progesterone; everything else is fairly similar
  • Women typically don't take enough testosterone
  • Women have a wreck of hormones after having a baby
    • Testosterone elevated to optimal levels helps everything else fall into place
  • Low dose = 2.5-4 mg

-Adam's preferred form of delivery for testosterone replacement…45:56

  • For men: 80% use testosterone cream (prescription needed), healthiest and safest means, no needles or gels
  • Doses can be adjusted based on where they feel the best
  • Injections: split dose throughout the week
  • It's one or the other (injection vs. cream) most of the time
  • Consistent application of small doses is far preferable to infrequent larger doses

-Why the vagina or scrotum isn't the best place to apply the cream…51:23

  • The best place to apply the cream is the back of the knee, forearms, or shoulders
  • It's where the highest concentration of testosterone is already located
  • Patients have reported imbalanced numbers after applying scrotally or vaginally

-Whether increased testosterone levels can deleteriously affect one's overall health…54:08

-The peptide stacks recommended by RenewLifeRX…1:00:19

-Why Adam wrote a book on controlling alcohol consumption…1:09:17

  • Adam's book: Better Than the Binge: Overcoming the Social Obligation of Alcohol
  • Chronic biohacker (keto diet, intermittent fasting, etc.)
  • Alcohol was always part of Adam's life; had an alcoholic father
  • Went on an alcohol fast for 30 days, then 60, then 90, decided to never drink again
  • There are benefits to microdosing on alcohol, provided it's not a “fall back”

-And much more…

Click here for the full written transcript of this podcast episode.

Scribe Writing (formerly known as Book In A Box)

Episode sponsors:

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Do you have questions, thoughts or feedback for Adam or me? Leave your comments below and one of us will reply!

Ask Ben a Podcast Question


98 thoughts on “Testosterone Replacement Therapy, Hormone Testing 101, Spot-Reducing Fat Loss Cream, The Benjamin Button Longevity Cocktail & Much More With Adam Lamb of RenewLifeRX.

  1. CJ says:

    We need clarification from Keith and others because a lot of what Adam said in this podcast is different from other popular opinions such as Jay Campbell’s, Keith Nicholas, Danny Bosa, and Lifting Dermatologist. I don’t want to hear Keith and Danny bicker. Obviously they’ve had a falling out or something, but the fact is most of the advice they preach is the same. Ben please get someone else that actually knows what they are talking about when it comes to TRT on your podcast ASAP.

  2. Ricky says:

    Just have Dr. Neal Rouzier on this subject. Ask him to see if he needs to refute anything that was stated on this podcast.

  3. Jerry Bailey says:

    Curious why you mentioned supplementing DHEA in the evening before bed? My understanding was that this was an early morning natural release and that it was best to time with the natural timing? Can you expand on the “why”? Thanks!

  4. Sam says:

    I am not an expert. Have never done TRT (but am interested in optimizing hormones). With my limited knowledge, I understand I will be unqualified to Adam to offer my opinion.

    With that said, I came here to see if there were any comments related to a few red flags I noticed. These are related to the relevance of free testosterone, thyroid, cycling off TRT, transscrotal application, estrogen, and not being the guy to discuss science (Danny Bossa outlines my thoughts and more).

    I am willing to accept that Adam has the real world experience, and knows probably knows his stuff. There was some good stuff in this podcast. However, I am completely unimpressed by the copy-and-paste comments being left here, and am having a hard time trusting his credibility.

    Ben, please have Danny Bossa on the show.

    And Danny, will check out your YouTube. Happy to have discovered you here.

    1. Danny Bossa says:

      Thank you, Sam! :)

    2. Adam says:

      Sam,

      Thanks for posting on here with some questions. Let me do my best to answer:

      1. When testing free testosterone and finding it to be low or high is the question is why? Through testing SHBG and total testosterone in we have a formula to figure out where that testosterone is. This has been proven countless times. We focus more on a total testosterone to SHBG ratio. This is all information conducted through our system for years. That’s all I can share on that specific topic.

      2. Thyroid, this is simple. The number is like 1/100 people actually have a thyroid problem that we see. Optimal testosterone and other hormone levels along with some lifestyle changes gets most lagging people’s thyroid back in healthy range/function. Thyroid medication the the most over lily prescribed drug and misdiagnosed hormone. Again, this is all first hand witness.

      3. Cycling off testosterone: I think this comment got way out of context. This is also dependent on where men are at in their life cycle (yes, your life goals are important)

      We like to offer people the option of coming off for 30 days 1-2 times a year. Many elect to do this because it allows them to see how they would be if they had to go off for some reason, it also allows us to show how we can take someone on healthy testosterone treatment off and get back at least the levels they started with. There is way to much detail in all the reasons and results here, but to sum it up, it’s about being responsible with the life of others.

      Testosterone scrotal application
      1. We have guys that go and do it and they are usually the guys that get side effects even after lowering the dose.
      2. Our goal isn’t most absorption, it’s safest effective care.
      3. Our team has read the studies (along time ago) and decided that is not a route they recommend.

      There are always some patients that decide to do their own thing, whether it is a scrotal application or sub-q injections (we also do not recommend) and end up going back to the recommended dosing and usually require our team to treat additional unwanted side effects.

      Another great reason to take a reset from testosterone is when it all seem out of whack.

      4. Estrogen, high estrogen is bad and so is low estrogen. I have never personally read a study that wasn’t completely flawed. Estrogen, like testosterone plays a major role in our psychology too. Sound mind, sound body. We believe in a healthy balance. Different people function better with different estradiol levels too. We see this, we hear this, and we pay attention to it in everyday patient practice, like real life, not a 10 year old study that is even close to how we practice.

      Hopefully that help shed some light to your questions. Please remember this is what our team does daily. We actually see hundreds of labs a month, connect with patients and ask questions on how they are monthly, the rechecking their labs to back up the health levels that are feeling.

      I would be curious to see Danny’s own blood work. I supply mine for the last 3 years (I do it quarterly)

      The proof is always in the blood work and the patient’s well being.

      1. Danny Bossa says:

        Adam Lamb are you for real??

        I can’t believe you’re actually saying this in a public space. Shouldn’t you be asking the “science people” to review what you’re saying before posting it for all to see?

        You’ve given me all I need to make a bro science video on my YT channel. I appreciate it!

        1. Adam says:

          Danny,

          Your videos drive traffic for us, thank you!

          Then we actually get to show people that what you state is wrong through blood work and regular patient monitoring.

          Then they are long term clients because they realize how false the noise is that got them to look into us.

          We are work with just shy of 100 PCPs throughout the country that refer and also monitor their clients we manage. Everyone getting healthier and happier.

          Best of luck with your videos

          1. Danny Bossa says:

            So, let me get this straight:

            Dr Eric Serrano
            Dr Mark Gordon
            Dr Jordan Grant
            Dr Brad Garner
            Dr Jeffery Ruterbusch
            Dr Ed Lichten
            Dr Barry Breger
            Broderick Chavez
            Jim Brown
            IFBB Pro John Meadows
            IFBB Pro Greg Doucette
            Etc

            You’re saying ALL these guys are wrong and you’re right? Is this a joke?

            You won’t debate me because you know you’d have your ass handed to you. Let’s have a debate on Ben Greenfield’s show if you a really are that convinced that what you are saying it true and can back it up with evidence. I’ll be doing a video ok my channel today regardless.

            Your message to me on FB:

            Hey Danny,

            Let me know if you would like to hop on a call. I’m not interested in some debate of egos and BS. I would however be interested in a conversation about different views, experience, etc.

            Saying that someone that doesn’t do things the way you do is wrong, is actually wrong. There are many ways to do something.

            Having an understanding of the “why” behind what we do and the outcomes we actually see (WE ACTUALLY SEE) may be interesting to you.

            Please let me know.

          2. Danny Bossa says:

            Here’s a video that will drive traffic! Or not?

            https://youtu.be/m9DH0JE6DA0

      2. Andy
        Danny is no expert but he does parrot what myself and others have told him. Unfortunately a lot of the information you discussed in your podcast is not evidence based medicine. I could spend the next hour typing why but I’m not sure it would have any effect. You can reach out to me anytime if you would like. I probably have more experience with the scrotal application than almost anyone in the TRT world.

        1. Danny Bossa says:

          Keith, aren’t you going to back to do webcasts with Jay Campbell now? Who also has zero medical training and parrots what everyone else says? What’s the difference exactly? It’s only ok if the person is promoting you? Is that how it works?

    3. Scott says:

      I would also support having Danny Bossa on the show. We need to hear all sides on this exciting yet controversial issue. There are a few schools of thought on the ideal HRT protocols and the interpretations of the various clinical studies on the effects of HRT on various health issues. Not to mention the whole topic of whether or not to control estrogen! You owe it to your audience to balance this scale now that you have opened the HRT Pandora’s box!

    4. Are you kidding? Danny is no expert. He has no medical training. He has no training interpreting labs. He has ZERO hours of clinical experience. He simply copies what he is told by the physicians he associates with. He is on constant dial a Doc when asked a question and then presents the information as if it were him.

      1. Danny Bossa says:

        Keith used to tell everyone and their mother that what we were doing was great (back when we supported him and his practice). Unfortunately, due to events outside our control we no longer associate with him. Once that took place suddenly we now know nothing (when we used to get high praise from him previously). Interesting how that works?

        Keith, you wanted to go out on your own, remember? Yet the only attention you get is from making comments on anything I do. If I’m so unimportant, why do you bother? You have an unhealthy obsession with me.

        You’re on your own, exactly as you wanted to be. So do your thing and I’ll do mine. At the end of the day we are both preaching the same thing. You know that and admitted it above.

        By the way everyone, even though I no longer associate with Keith, I learned at half of what I know from him, which he probably learned from Dr Neal Rouzier. At the end of the day, everything everyone does is something they are parroting that they have learned from someone else, including every single word I have typed here.

        1. Danny
          I have spent over 15 years learning for myself. Rouzier is my mentor but I have spent years and hundreds of hours researching on my own. Believe it or not I also send Rouzier articles as he does me. It is a 2 way street and we are friends. Danny I have been doing this for a long while and was “on my own” well before you. So I learned from others but I have also put in the sweat equity. You know that. I focus on BHRT in men and women and that is our passion. The direction and patient population that we are focused on is so different from the audience you reach.

        2. Oh to answer your question about why do I bother.
          1. Some of the medical information you provide on forums can be incorrect and there have been many instances where you are practicing without a license which is illegal. You cannot give specific advice on dosages of testosterone or thyroid for instance. There have been 2 men who have contacted me saying they took your advice and “got worse”. You are liable whether you realize it or not
          2. The answer is not always “increase free T”. You have no medical training and not one single hour of clinical experience. There is so much more involved than labs and free T. One has to consider past medical history, review of systems, present medical conditions, psychosocial issues, any many other factors. None of this can be done on a forum
          3. Some of your content done with Steven on YouTube to increase viewership Makes our jobs harder. Anabolic steroids as a part of female hormone optimization? Really? Anabolic steroids in general? Guest presented as experts who have NO medical training including one who’s clinics are presently being investigated by the DEA. I could go on with many more but won’t.

          But luckily you viewership is usually less than 1k and hardly ever more than 2k so it is a very small viewership and the population you are catering to is not really the patient population that we are focused on.

          1. Danny Bossa says:

            So I guess everyone on T-Nation, Excel Male, all Facebook groups, all TRT related discussion social media platforms should all be sued as well as all of their members for exchanging advice. Heck, even Ben Greenfield should be sued in that case, right? Aren’t you doing stuff with Jay Campbell now? Will you be suing him also?

            Do you realize how ridiculous you’re being?

        3. Danny,
          You are missing the point. You cannot give specific dosage advice. Ben does not. Jay does not. They give general advice. Problem is Danny is that you have No medical training and you are giving very specific advice and you are many times wrong. It has taken decades to understand what I do and I’m still learning. The forums you listed are where you belong…
          ExcelMale, T nation, and the Fb group.
          Those are not anywhere near the population of men and women we want to service.
          Good luck to you and I hope you get the ego gratification you so desperately crave. We wish you no ill will. Thanks for promoting no AI.
          Danny, our practice is totally different than the ones you associate with. We have a different purpose and are involved in research and writing.
          So no hard feelings we wish you success

          1. Danny Bossa says:

            If you really did mean everything you just wrote here, you should give me a call. I know you won’t, because you are as stubborn if not more stubborn than I am, But you should anyway.

          2. CJ says:

            Keith come on man really!??!? This is not rocket science and who give a flying fuck if Danny is not a doctor. Ben Greenfield is not a Doctor and is probably smarter than both of you combined. All of the information Danny is talking about on his channel is essentially the same views as yours. This podcast with Adam Lamb is basically a joke with so much incorrect information.I hope that YOU will go on Ben’s show and talk Testosterone!

    5. Rob says:

      There is another route of HRT administration…. pelleting. We operate a wellness and aesthetics clinic and use the BioTE method/protocol. I’m also a patient and have a lot of experience using topicals, injectables and pellets. Pellets are by far the most efficient and effective route of administration. BioTE has over 10 years and 1.5 million pellet patients being monitored and following the BioTE protocol with great success. Very disappointed this alternative method wasn’t discussed.

  5. Danny Bossa says:

    I’ve made other replies to comments here but they have also been deleted. Perhaps it’s a bug in the system that targets Italians? ;-) I won’t bother re-typing again fruitlessly. It’s all yours guys.

    1. It was the length again that triggered the spam filter. You should see it now.

  6. Campbell says:

    Adam Lamb:

    Will you please address the post by Danny Bossa that seems to contradict many of your perspectives presented in the podcast? I have no idea who this Bossa guy is or if there is any credibility to his post, but I find it odd that his post keeps appearing and then disappearing again.

    Is it getting taken down because his points are invalid? Is his advice hurting people? Or is he just another one of these “look at me” trolls?

    1. Jamie says:

      No, its scientifically based facts that contradict what Adam claimed.

      1. Campbell says:

        Thanks Jamie – do you have the science to share? Please post links if you do. Otherwise you appear to be another troll like this Bossa guy may be. I haven’t seen him post any links either.

        I was really hoping for some dialogue with Adam Lamb but I don’t see Bossa’s post any longer.

        1. Jamie says:

          Feel free to join “TRT and Hormone Optimization” Facebook group.
          You will find no less than 4 doctors & several TRT/HRT clinic owners in the group that regularily offer FREE advice.
          Go to the “Files” section & there are dozens of medical research & articles backing up what is preached there.
          Use the search function and look up AI’s or protocols or any of a hundred topics and you will get researched based & backed information. They also have a YouTube channel with even MORE topics & more doctors interviewed. The group is a wealth of knowledge. CORRECT knowledge

        2. Danny Bossa says:

          Hi Campbell,

          I’m the furthest thing from a troll as they come.

          Take a look (perhaps ignore the spoof video I did yesterday as that’s a LONG storey) ;-)

          https://www.youtube.com/channel/UCoLNk-4LAYsbfsQwjFWG2gQ/videos

      2. adam says:

        Jamie, how many patients have you worked with for the last decade? How many actual people following what your “scientifically based facts” protocols do you speak with? What technology do YOU to measure and manage these people?

        For example: I had a guy send me study claiming that scrotum application was best. The men in the study were all post nandrolone abuse… with post steroid abuse testosterone levels. That isn’t our patient, but good info. Just not super relevant.

        Jamie, how long have you been on TRT? How long have you been doing the scrotum application?

        1. Jamie says:

          I dont need to give you MY resume. I happen to be a well educated health professional (Advanced Care Paramedic), who can decipher biological studies and understand biological processes.
          The fact you preach 6 month “cycles” (my phrase) of TRT is ridiculous to anyone who understands anything about hormones & feedback systems.
          Debate Danny Bossa.
          Dont hide behind excuses.
          Or one of the 6 or more experts in the TRT and Hormone Optimization group.
          I dont contend to be an expert, I trust Danny & the other experts & my knowledge smells your bullshit from a mile away

          1. Adam says:

            Jamie, how long have you been on TRT? How long have you been doing the scrotum application?

            Still waiting on this answer.

        2. Jamie says:

          Despite your assertion that Danny has no experience, I contend you are afraid a “non-expert” might school you in the topic with logic, common sense & science.

          1. Adam says:

            Thanks, Jamie! Your comments help your cause…

        3. Jamie says:

          I dont do scrotal cream.
          I do IM injections.
          How Long I have been on trt Is of no relevance either. Oh, but I have no problem saying not very long.
          Once again, my resume has nothing to do with this conversation, either in profession or as a patient’s, because I’m not the person in question. I know biology, I know chemistry, I know hormones, and I know that the information from Danny and the other experts is much more accurate than your information.

          1. Adam says:

            Jamie,

            You are commenting though, correct? I just like to have a good understanding of things by asking lots of questions, in all situations.

            I’m not asking you to defend yourself, that’s not how I roll. I just like to make sure I understand the person I am communicating with.

            Is it fair to say you believe scrotal application is best but you don’t do it?

            That is a bit confusing. Why do t you follow Danny’s advice if it is so great?

            Also, I have seen lots of guys have a great experience with TRT for a year or even two and then have issues serious health issues because the “big picture” was t taken into account.

            I hope you stay safe and healthy based on the advise you are currently receiving.

          2. Jamie says:

            No Adam,
            I have no opinion on scrotal cream.
            Not sure why you are targeting in on that one topic?
            There was a lot more discussed than scrotal cream.

          3. Jamie says:

            Adam, I dont follow “Danny’s advice” per se…. I follow the advice of several doctors & experts (Danny being one of at least 6) that advocate protocols & scientific reasoning for those protocols.
            It’s nice you have antedotal success, but it doesnt jive with OTHER antedotal evidence nor actual medical proof and logic

        4. Danny Bossa says:

          Adam,

          Since you enjoy challenging people’s credentials when they ask questions, perhaps you can take a step back and realize you are not a physician yourself and have zero medical training? You’re a business owner. You admitted it in the interview that you don’t know much about the ‘science’ behind it. Just a thought.

          1. Sam says:

            The endocrinologist in my network is highly knowledgeable, but I also know he wouldn’t venture outside the conventional standard of care. What are the alternatives for someone like me who is clinically healthy? Read up on Reddit and pubmed research, self-administer with internet-sourced T, or see a seemingly qualified clinic like Adam’s? I don’t very many good options.

          2. Jamie says:

            Sam,

            If you are clinically healthy & do not have symptoms of low Testoaterone, stay away!

            TRT is a lifetime commitment.

            I would love to not have to do it. But my day to day life was terrible & it’s great TRT is somewhat available to us (depending on location it can be hard to get Rx’d)

            TRT should not be used by young healthy people.

            Why would you shut down your own, properly working hormone system if you dont have to?

            If you are clinically healthy & not suffering low T symptoms be thankful

    2. adam says:

      Hey Cambell,

      Sorry for the delayed response on these.

      Danny wanted to have me on his podcast to debate him and I respectfully declined. I asked him for HIS experience in the space and he had none. We love communicating with other experts to see the success other doctors or clinics are having. In most cases, they are asking how they can get the results we do (literally 3 inquiries today)

      #1 priority is always getting people healthier and happier.

      There are many ways to do lots of things. We have had a lot of success helping thousands people get healthier and feel great.

      For example, 80% of our client base won’t even consider a needle. We treat regular people that want to be healthier and feel great with out also feeling like a science project.

      I have been in this space for a long time, I have seen many “next best things” the one thing that is consistent, is our patients results. Our panel of doctors will not completely change what they believe because of a Youtuber that reads a lot. So do they, they also have the years of data of thousands of patients to back up what is believed on our end.

      Also, some things mentioned in the comments, that we do not do as “standard practice” does not mean we are not currently researching it or have in the past. Maybe we are actually further a head…

      Hopefully this helps answer your questions.

      Have a blessed weekend.

  7. Bob B says:

    This has got to be one of the worst podcasts you have put out. So much misinformation.

    What proof of this do have you ask? Stop deleting comments to find a detailed listing.

    1. adam says:

      Hey Bob,

      Sorry for the delayed response.

      #1 priority is always getting people healthier and happier.

      Thanks for all the great feedback. It is awesome that you have taken the time to share your opinion.

      Is your opinion based on patients at a practice you work with? Like have you been able to witness the success of peoples care for year after year? our studies that you have read with zero involvement?

      There are many ways to do lots of things. We have had a lot of success helping thousands people get healthier and feel great.

      For example, 80% of our client base won’t even consider a needle. We treat regular people that want to be healthier and feel great with out also feeling like a science project.

      I have been in this space for a long time, I have seen many “next best things” the one thing that is consistent, is our patients results. Our panel of doctors will not completely change what they believe because of a Youtuber that reads a lot. So do they, they also have the years of data of thousands of patients to back up what is believed on our end.

      Also, some things mentioned in your comments, that we do not do as “standard practice” does not mean we are not currently researching it or have in the past. Maybe we are actually further a head…

      Hopefully this helps answer your questions.

      Have a blessed weekend.

  8. Spence says:

    Can anyone comment on the safety of the creams being used as the transdermal vehicle for absorption? At one point I looked into Lipoderm, which is supposed to be a more natural cream, and some of the ingredients seem concerning for long term use…

    Water

    Isopropyl Myristate

    Phospholipids

    Cetearyl Alcohol

    Triticum Vulgare (Wheat) Germ Oil

    Cetyl Alcohol

    Stearyl Alcohol

    Ceteareth-20

    Caprylic/Capric Triglycerides

    Glycerin

    Dimethicone

    C13-14 Isoparaffin

    Laureth-7

    Xanthan Gum

    Magnesium Aluminum Silicate

    Polyacrylamide

    Disodium EDTA

    BHT

    Phenoxyethanol

    Methylchloroisothiazolinone

    Methylisothiazolinone

    1. adam says:

      That is a lot of ingredients…

  9. Eddie R says:

    This is spot on!

    1. Eddie R says:

      That’s weird commented on a Danny Bossa comment and now deleted again?

      1. adam says:

        Hey Eddie R,

        Sorry for the delayed response.

        #1 priority is always getting people healthier and happier.

        Thanks for all the great feedback. It is awesome that you have taken the time to share your opinion.

        There are many ways to do lots of things. We have had a lot of success helping thousands people get healthier and feel great.

        For example, 80% of our client base won’t even consider a needle. We treat regular people that want to be healthier and feel great with out also feeling like a science project.

        I have been in this space for a long time, I have seen many “next best things” the one thing that is consistent, is our patients results. Our panel of doctors will not completely change what they believe because of a Youtuber that reads a lot. So do they, they also have the years of data of thousands of patients to back up what is believed on our end.

        Also, some things mentioned in the comments, that we do not do as “standard practice” does not mean we are not currently researching it or have in the past. Maybe we are actually further a head…

        Hopefully this helps answer your questions.

        Have a blessed weekend.

        1. Eddie R says:

          Hey Adam thanks for the response. Not sure why you feel and copy and paste response to everyone is the way to go. Also not sure why someone has to own a clinic in order to have the knowledge and go up against you. You “respectfully” declined Danny’s invitation because why….you know you would get crushed? You couldn’t even answer some of Ben’s questions and the entire podcast was about you and your business. You keep repeating that you have helped many patients over the years but that doesn’t provide us with fact base answers. It is just us needing to take your word for it? That’s not how it works Adam. How can you dispute fact base medical research? If you will not go on Danny’s YouTube channel then have Ben mediate a debate between you two. What do you have to lose? Oh your entire business.

          1. Adam says:

            eddie,

            Will you share your current TRT protocol?
            How long have you been TRT yourself?

            One of the things our umbrella company does is consult for other practices to help set them up with our process, technology, and PATIENT OUTCOMES. Why? Because they are great!

            If you don’t have access to patient outcomes how can you be an expert?

            If you don’t have years of data monitoring the long term care (3+ years) of people then you probably shouldn’t be telling them what to do. Just my thought.

            A person that just reads studies but has no pulse on the studies or a way to run a trial and measure the outcomes is just a guy with an opinion.

            Sorry we see things differently.

  10. Danny Bossa says:

    Hi Ben,

    I’m Danny Bossa, the guy who has the TRT and Hormone Optimization YouTube channel. My partner is Steven ‘The Lifting Dermatologist’ Devos from Belgium. I said I’d listen to the podcast you did and then fill you in as to what was demonstrably false. Again, not just anecdotally false. Demonstrably false as in it contradicts everything in the medical literature.

    I apologize for not having had listened to many of your podcasts before. However, it was clear as day that you knew significantly more than Adam did on the subject. When you asked about free testosterone when he only mentioned total. When you brought up scrotal cream and was talking about application anywhere else but. When you brought up his peptides only to have him say, “I leave that to the smart science guys.. I just handle the business side”. I’m thinking, “Then why are you giving a talk on the science??”

    Bullet points of what was incorrect (and I removed several because it got too long and it is STILL too long). Enough for us to spend probably 2 hours discussing if you wanted to:

    • He claimed total testosterone was more important than free testosterone. This is false. Total testosterone is the combination of bound and unbound testosterone. 98% of it is bound to SHBG and Albumin (you know this). Take two guys with total T of 800. One has low SHBG and the other has high SHBG. One has a free T of 30 ng/dL and the other has a free T of 8 ng/dL. Same total, but the guy with 30 feels a hell of a lot better than the guy with 8! This is why FREE T is the most important piece here. Total is virtually irrelevant.

    • You can’t just measure TSH for thyroid. At the very least you need Free T3 and Free T4. He made it sound like optimizing thyroid is unnecessary. It is absolutely necessary for many, many guys and oftentimes the reason TRT isn’t working for them in the first place.

    • When you are measuring hematocrit and hemoglobin, you measure platelets as well. Elevated hematocrit and hemoglobin are normal and to be expected on TRT (this is called Erythrocytosis). It’s only when platelets get out of control can it be dangerous (Polycythemia Vera) which is actually a form of cancer. One doesn’t turn into the other. Plenty of athletes use compounds like EPO to raise h/h to have better oxygenation of the blood = better performance. Higher levels of h/h are a non-issue. No need for phlebotomy whatsoever.

    • He said TRT is not a permanent solution. Huh? Let’s get the guy’s T levels optimized, feeling great, all symptoms resolved. Then let’s take him off T with suppressed natural production? Let it take 6 months for his levels to ‘maybe’ come back to healthy levels? This is nuts. TRT is for life. Any clinic that tells a patient that they can do this temporary are lying to their patients. You also do NOT STOP TRT every 6 months to ‘reset’ your body. No idea where he came up with that.

    • He claims he wants to do ‘responsible TRT’ yet he blocks estrogen? He claimed estrogen is related to inflammation! What!? Please do show the evidence for this in the literature. Roughly half of the benefits you get from TRT is from the conversion to estrogen. Libido, erections, bone mineral density, cognition, cardiovascular health, reduced risk for diabetes and Alzheimer’s, reduced chance of stroke, etc. etc. All from Estrogen! Not to mention, it has a direct impact on muscle growth! He says he doesn’t feel good unless he takes an AI. This is due to a poor protocol and zero understand of the action of estrogen in men. Every single doc I work with doesn’t block estrogen. We’re talking a combined tens of thousands of patients. Not one of them on an AI. He said he measured bone mineral density after a few months with a guy on an AI. You won’t see this after a few months. An AI is a slow poison that destroys endothelial and cardiovascular function, and tons more, over time. Never, ever block E2.

    • He claimed that FSH and LH don’t do down with the cream. This is beyond nonsense. ANY exogenous testosterone will eventually crash natural production.

    • The scrotal application is the undisputed BEST application site (you knew this too and he didn’t). 8 times greater absorption compared to anywhere else (lots of literature on this). Back of the knees? Guess he just wants to sell more cream to his patients because they will need to apply significantly more. He’s worried that scrotal will affect his balls. I couldn’t believe it! It is the scrotal SKIN that is absorbing the cream, not his balls! He also said it converted MORE to estradiol than other application sites which is also false. If anything, we are seeing the cream convert LESS to estradiol compared to injections. Lots of talk about why scrotal is bad meanwhile he has never done it himself and never actually tried it at his practice. Plus, you get a boost in DHT due to higher levels of 5-Alpha-Reductase in scrotal skin. Ignorance at its best.

    • 300mg of injections every 3 weeks causes cardiovascular disease? (agreed that it is a stupid protocol) I will give him the keys to my house if he can prove this (he can’t, because it is nonsense). Testosterone has been studied for over 80 years. In every study, no harm was found regardless of the dose or frequency.

    I have no business angle here. I help guys for free. I have a business that has nothing to do with this stuff. Misinformation on this subject angers me because guys learn ‘bro science’ and wind up feeling like crap. I want guys to feel better. It’s my way of giving back from all the guys who helped me.

    You probably already knew half this stuff. I can teach you the other half. Explain it to your viewers in simple English and demonstrate it with logic and common sense. Literature to back up any of it upon request.

    1. adam says:

      Danny,

      I think it would good to explain to you the differences in what you are claim are best and what we see.

      The challenge is your approach to the “conversation”. If you were more inviting to communicate with I would be much more excited to explain to you what we see.

      The biggest hole in the claims I see from you is how the patient actually feels. What is your patient retention rate?
      (ours 86%men 93% women)

      We communicate with our patients every 2 weeks and not one question is ever about their bench press or PR. We look at labs initial, 90 days, 6 months and then every 6 months. What are your protocols for care?

      It sounds like it is “just rub a bunch of cream on your scrotum because i said so.” That sounds scary to me…

      Wishing you the best.

      1. Danny Bossa says:

        From all the points I made, this is all you understood:

        “just rub a bunch of cream on your scrotum because i said so.” That sounds scary to me…

        You’re forgetting that I interview the best doctors in the world. I speak the majority of them on almist daily basis. The things you are claiming here is called ‘bro science’ and the comments are reflecting it.

        I felt great when I used to smoke a half pack of cigarettes a day. Doesn’t mean they were good for me! Health is the primary focus and then ensuring the patient is symptom free. You’re instance of blocking estrogen, taking a month off from TRT, focusing on total instead of free, claiming thyroid doesn’t need to be addressed in lost cases is in absolute and complete contradiction to what the very best in the world are doing, to what we are seeing among the men we help, and lost importantly the medical literature.

        My comments were not an invitation to have a discussion with you by phone for me to listen to the reasons why you feel you’re doing it the correct way. Your methods can be demolished in 5 minutes with logic alone. My comments here were to ensure that whoever listened to this took it with a grain of salt and did not, for one moment, consider attempting at some of the things you suggest.

        If anything, my comments were a heads up to Ben Greenfield, as everyone else stated, that the content of this podcast was essentially How Not To Do TRT 101 as I’m certain that he is just as adamant about his concerns of misinformation on his platform as I am on mine.

      2. Danny Bossa says:

        We recorded the video today. It will be uploaded in the next 48 hours.

        1. Danny Bossa says:

          Here it is… Hope you enjoy it 😁

          https://youtu.be/m9DH0JE6DA0

    2. Adam says:

      Danny,

      RESPONSES ARE IN BOLD, ENJOY. 😊

      • He claimed total testosterone was more important than free testosterone. This is false. Total testosterone is the combination of bound and unbound testosterone. 98% of it is bound to SHBG and Albumin (you know this). Take two guys with total T of 800. One has low SHBG and the other has high SHBG. One has a free T of 30 ng/dL and the other has a free T of 8 ng/dL. Same total, but the guy with 30 feels a hell of a lot better than the guy with 8! This is why FREE T is the most important piece here. Total is virtually irrelevant.

      THATS LIKE THE 5 YEARS AGO BELIEF. I CONTRACTUALLY AM NOT EVEN ALLOW TO EPLAIN THIS WITHOUT AN AGGRESSIVE NDA. THE STUFF WE ARE DOING IN THE FREE-TEST SHBG AREA IS NEXT LEVEL, FOR A GUY THAT JUST READS OLD STUDIES I WOULDN’T EXPECT YOU TO UNDERSTAND.

      • You can’t just measure TSH for thyroid. At the very least you need Free T3 and Free T4. He made it sound like optimizing thyroid is unnecessary. It is absolutely necessary for many, many guys and oftentimes the reason TRT isn’t working for them in the first place.

      THYROID IMPROVES WITH OPTIMAL TESTOSTERONE LEVELS.

      • When you are measuring hematocrit and hemoglobin, you measure platelets as well. Elevated hematocrit and hemoglobin are normal and to be expected on TRT (this is called Erythrocytosis). It’s only when platelets get out of control can it be dangerous (Polycythemia Vera) which is actually a form of cancer. One doesn’t turn into the other. Plenty of athletes use compounds like EPO to raise h/h to have better oxygenation of the blood = better performance. Higher levels of h/h are a non-issue. No need for phlebotomy whatsoever.

      98% OF OUR PATIENTS DO NOT GET HIGHER THAN NORMAL HEMO, RBC, or HEMATOCRIT . YOUR COMMENT IS BASED ON NOT KNOWING WHAT YOU ARE DOING OR TALKING ABOUT. THE HUNDREDS OF BLOODWORK WE SEE EACH MONTH BACK UP MY STATEMENT. ARE YOU CLAIMING LABCORP HAS A CONSPIRACY AGAINST OUR PATIENT OUTCOMES? THAT IS LITERALLY HOW RIDICULOUS YOUR COMMENTS SOUND.

      • He said TRT is not a permanent solution. Huh? Let’s get the guy’s T levels optimized, feeling great, all symptoms resolved. Then let’s take him off T with suppressed natural production? Let it take 6 months for his levels to ‘maybe’ come back to healthy levels? This is nuts. TRT is for life. Any clinic that tells a patient that they can do this temporary are lying to their patients. You also do NOT STOP TRT every 6 months to ‘reset’ your body. No idea where he came up with that.

      WE DO TRT RESPONSIBLY AND PATH VARIES 100% BASED ON THE PATIENT. ANYONE PRESCRIBING THIS AS A “life sentence” IS CARELESS OR DOESNT KNOW WHAT THEY ARE DOING.

      • He claims he wants to do ‘responsible TRT’ yet he blocks estrogen? He claimed estrogen is related to inflammation! What!? Please do show the evidence for this in the literature. Roughly half of the benefits you get from TRT is from the conversion to estrogen. Libido, erections, bone mineral density, cognition, cardiovascular health, reduced risk for diabetes and Alzheimer’s, reduced chance of stroke, etc. etc. All from Estrogen! Not to mention, it has a direct impact on muscle growth! He says he doesn’t feel good unless he takes an AI. This is due to a poor protocol and zero understand of the action of estrogen in men. Every single doc I work with doesn’t block estrogen. We’re talking a combined tens of thousands of patients. Not one of them on an AI. He said he measured bone mineral density after a few months with a guy on an AI. You won’t see this after a few months. An AI is a slow poison that destroys endothelial and cardiovascular function, and tons more, over time. Never, ever block E2.

      HEALTHY ESTROGEN LEVELS ARE GOOD. HIGH IS BAD AND SO IS LOW. THERE ARE WAY MORE STUDIES SUPPORTING THIS PROOF OVER YOUR OPINION OR STUDIES OF GUYS ON AI THAT ARE NOT EVEN ON TESTOSTERONE, I HAVE SEEN YOUR REFERENCES. LAUGHABLE

      • He claimed that FSH and LH don’t do down with the cream. This is beyond nonsense. ANY exogenous testosterone will eventually crash natural production.

      I COULD LITERALLY SHOW YOU 50 CASES OF MEN BETWEEN 30 and 40 WITH THE SAME LH and FSH AS WHEN THEY STARTED ON OUR CREAM. WHY? WE KNOW WHAT WE ARE DOING. LITERALLY SEEING THEIR BLOOD WORK (science bro)

      • The scrotal application is the undisputed BEST application site (you knew this too and he didn’t). 8 times greater absorption compared to anywhere else (lots of literature on this). Back of the knees? Guess he just wants to sell more cream to his patients because they will need to apply significantly more. He’s worried that scrotal will affect his balls. I couldn’t believe it! It is the scrotal SKIN that is absorbing the cream, not his balls! He also said it converted MORE to estradiol than other application sites which is also false. If anything, we are seeing the cream convert LESS to estradiol compared to injections. Lots of talk about why scrotal is bad meanwhile he has never done it himself and never actually tried it at his practice. Plus, you get a boost in DHT due to higher levels of 5-Alpha-Reductase in scrotal skin. Ignorance at its best.

      HOW LONG HAVE YOU BEEN ON TRT DANNY?

      HOW LONG HAVE YOU BEEN DOING THE SCROTAL APPLICATION?

      DO YOU BELIEVE HIGH DHT LEVELS IS GOOD FOR MEN?

      WHAT IS YOUR CURRENT HAIR STYLE?

      MOST MEN DONT WANT TO RUB CREAM ON THEIR SCROTUM.

      • 300mg of injections every 3 weeks causes cardiovascular disease? (agreed that it is a stupid protocol) I will give him the keys to my house if he can prove this (he can’t, because it is nonsense). Testosterone has been studied for over 80 years. In every study, no harm was found regardless of the dose or frequency. NOT SURE WHAT THIS COMMENT IS REFERENCE TOO?

      1. Danny Bossa says:

        TRT does not fix thyroid. This is basic biology.

        LH/FSH gets suppressed within 6 weeks with any administration of T. Again, basic biology.

        Video getting posted within 48 hours. What you are stating is malpractice.

      2. Danny Bossa says:

        As per Dr Mark Gordon who I’m telling this about, and is clearly having a giggle:

        Topical Testosterone converts to DHT because of the presence of 5AR in the pilosebaceous organelle in the skin. DHT is three times more suppressive of LH than Testosterone. Also, DHT levels are directly correlated to the rise in PSA.

        No, you can’t have non suppressed LH/FSH with cream. It is a complete and utter impossibility. You might as well be telling me the patients can breathe underwater.

  11. Kevin says:

    Wow, there is so much miss information here I couldn’t help not commenting. It made me laugh!

    And WHY was Danny Bossa’s comment deleted?

    1. His comment wasn't intentionally removed and has been restored. Apparently really long comments can get flagged as spam and automatically deleted. Working with our IT dept to fix this!

      1. Adam says:

        Hey Ben,

        Sorry for the delay with responding to some of the comments from Danny and his crew.

        I think they/he has many important opinions, just not sure how well he has actually been able to show “proof in concept” with those.

        What we do is data based. We have recently been approached by a major technology company in the healthcare space for a JV on how we collect , manage, and treat based on data. Our patients, our protocols, our experts.

        We appreciate the opinions of others. Thanks again for the time on the podcast, you are great!

    2. Adam says:

      Hey Kevin,

      Sorry for the delayed response.

      #1 priority is always getting people healthier and happier.

      Thanks for all the great feedback. It is awesome that you have taken the time to share your opinion.
      There are many ways to do lots of things. We have had a lot of success helping thousands people get healthier and feel great.

      For example, 80% of our client base won’t even consider a needle. We treat regular people that want to be healthier and feel great with out also feeling like a science project.

      I have been in this space for a long time, I have seen many “next best things” the one thing that is consistent, is our patients results. Our panel of doctors will not completely change what they believe because of a Youtuber that reads a lot. So do they, they also have the years of data of thousands of patients to back up what is believed on our end.

      Also, some things mentioned in your comments, that we do not do as “standard practice” does not mean we are not currently researching it or have in the past. Maybe we are actually further a head…

      Hopefully this helps answer your questions.

      Thanks,

      Have a blessed weekend.

      1. Jamie says:

        FML Adam, stop copy & pasting your responses. 🙄
        Is that your protocol regime too?

  12. Eddie R says:

    Ben or Ben’s assistants is there any reason why Danny Bossa comments keep getting taken down? As an avid listener and follower of Ben Greenfield I would think only accurate information should be posted. So Adam may have dupped Ben but there is an opportunity to fix. Keep Danny’s comments up or have Adam and Danny debate the information on the show. Let’s have it!

  13. Carson says:

    Why are Danny’s comments being deleted? Can’t handle being called out on this nonsense?

  14. Chad says:

    Wow. Ben. You should be very careful endorsing this individual. Some much misinformation and dangerous advice. This guy cares about the mighty dollar and not his clients. Clearly he is 20 years behind on the scientific literature. Absolute garbage…get real expert…there aren’t many but if you do your due diligence you’ll be able to find them.

    1. Adam says:

      Hey Chad,

      Sorry for the delayed response.

      #1 priority is always getting people healthier and happier.

      Thanks for all the great feedback. It is awesome that you have taken the time to share your opinion.

      Is your opinion based on patients at a practice you work with? Like have you been able to witness the success of peoples care for year after year? our studies that you have read with zero involvement?

      There are many ways to do lots of things. We have had a lot of success helping thousands people get healthier and feel great.

      For example, 80% of our client base won’t even consider a needle. We treat regular people that want to be healthier and feel great with out also feeling like a science project.

      I have been in this space for a long time, I have seen many “next best things” the one thing that is consistent, is our patients results. Our panel of doctors will not completely change what they believe because of a Youtuber that reads a lot. So do they, they also have the years of data of thousands of patients to back up what is believed on our end.

      Also, some things mentioned in your comments, that we do not do as “standard practice” does not mean we are not currently researching it or have in the past. Maybe we are actually further a head…

      Hopefully this helps answer your questions.

      Have a blessed weekend.

  15. Danny Bossa says:

    • He claimed total testosterone was more important than free testosterone. This is false. Total testosterone is the combination of bound and unbound testosterone. 98% of it is bound to SHBG and Albumin (you know this). Take two guys with total T of 800. One has low SHBG and the other has high SHBG. One has a free T of 30 ng/dL and the other has a free T of 8 ng/dL. Same total, but the guy with 30 feels a hell of a lot better than the guy with 8! This is why FREE T is the most important piece here. Total is virtually irrelevant.

    • You can’t just measure TSH for thyroid. At the very least you need Free T3 and Free T4. He made it sound like optimizing thyroid is unnecessary. It is absolutely necessary for many, many guys and oftentimes the reason TRT isn’t working for them in the first place.

    • When you are measuring hematocrit and hemoglobin, you measure platelets as well. Elevated hematocrit and hemoglobin are normal and to be expected on TRT (this is called Erythrocytosis). It’s only when platelets get out of control can it be dangerous (Polycythemia Vera) which is actually a form of cancer. One doesn’t turn into the other. Plenty of athletes use compounds like EPO to raise h/h to have better oxygenation of the blood = better performance. Higher levels of h/h is a non-issue. No need for phlebotomy whatsoever.

    • He said TRT is not a permanent solution. Huh? Let’s get the guy’s T levels optimized, feeling great, all symptoms resolved. Then let’s take him off T with suppressed natural production? Let it take 6 months for his levels to ‘maybe’ come back to healthy levels? This is nuts. TRT is for life. You don’t stop TRT every 6 months to allow your body to ‘reset’.

    • He claims he wants to do ‘responsible TRT’ yet he blocks estrogen? He claimed estrogen is related to inflammation! What!? Please do show the evidence for this in the literature. Roughly half of the benefits you get from TRT is from the conversion to estrogen. Libido, erections, bone mineral density, cognition, cardiovascular health, reduced risk for diabetes and Alzheimer’s, reduced chance of stroke, etc. etc. All from Estrogen! Not to mention, it has a direct impact on muscle growth! He says he doesn’t feel good unless he takes an AI. This is due to a poor protocol and zero understand of the action of estrogen in men. Every single doc I work with doesn’t block estrogen. We’re talking a combined tens of thousands of patients. Not one of them on an AI. He said he measured bone mineral density after a few months with a guy on an AI. You won’t see this after a few months. An AI is a slow poison that destroys endothelial and cardiovascular function, and tons more, over time. Never, ever block E2.

    • He claimed that FSH and LH don’t do down with the cream. This is beyond nonsense. ANY exogenous testosterone will eventually crash natural production.

    • The scrotal application is the undisputed BEST application site (you knew this too and he didn’t). 8 times greater absorption compared to anywhere else (lots of literature on this). Back of the knees? Guess he just wants to sell more cream to his patients because they will need to apply significantly more. He’s worried that scrotal will affect his balls. I couldn’t believe it! It is the scrotal SKIN that is absorbing the cream, not his balls! He also said it converted MORE to estradiol than other application sites which is also false. If anything, we are seeing the cream convert LESS to estradiol compared to injections. Lots of talk about why scrotal is bad meanwhile he has never done it himself and never actually tried it at his practice. Plus you get a boost in DHT due to higher levels of 5-Alpha-Reductase in scrotal skin. Ignorance at its best.

    • 300mg of injections every 3 weeks causes cardiovascular disease? (agreed that it is a stupid protocol) I will give him the keys to my house if he can prove this (he can’t, because it is nonsense). Testosterone has been studied for over 80 years. In every study, no harm was found regardless of the dose or frequency.

    1. Adam says:

      Hey Danny,

      Sorry for the delayed response.

      #1 priority is always getting people healthier and happier.

      Thanks for all the great feedback. It is awesome that you have taken the time to share your opinion.

      Is your opinion based on patients at a practice you work with? Like have you been able to witness the success of peoples care for year after year? our studies that you have read with zero involvement?

      There are many ways to do lots of things. We have had a lot of success helping thousands people get healthier and feel great.

      For example, 80% of our client base won’t even consider a needle. We treat regular people that want to be healthier and feel great with out also feeling like a science project.

      I have been in this space for a long time, I have seen many “next best things” the one thing that is consistent, is our patients results. Our panel of doctors will not completely change what they believe because of a Youtuber that reads a lot. So do they, they also have the years of data of thousands of patients to back up what is believed on our end.

      Also, some things mentioned in your comments, that we do not do as “standard practice” does not mean we are not currently researching it or have in the past. Maybe we are actually further a head…

      Hopefully this helps answer your questions.

      Have a blessed weekend.

  16. Jamie says:

    Why was Danny Bossa’s comment deleted?
    My understanding was he tried to correct orcquestion the mis-information presented?

  17. Jamie Thoms says:

    Danny is correct. Please, don’t allow information like this to to become widespread.

    1. Jamie says:

      Since he deleted Danny’s comment this information is going to be taken as true.
      It’s a damn shame. Guys are in for a hell of a bad time with this advice

    2. Jamie says:

      Danny re-posted… let’s see how long until its deleted again…..

  18. Danny Bossa says:

    Hi Ben,

    I’m Danny Bossa, the guy who has the ‘TRT and Hormone Optimization YouTube channel’ along with my partner Steven ‘The Lifting Dermatologist’ Devos from Belgium. Much of what was said in this podcast was demonstrably false. Again, not just anecdotally false. Demonstrably false as in it contradicts everything in the medical literature.

    I apologize for not having had listened to many of your podcasts before. However, it was clear as day that you knew significantly more than Adam did on the subject. When you asked about free testosterone when he only mentioned total. When you brought up scrotal cream and was talking about application anywhere else but. When you brought up his peptides only to have him say, “I leave that to the smart science guys.. I just handle the business side”. I’m thinking, “Then why are you giving a talk on the science??”

    Bullet points of what was incorrect (and I removed several because it got too long and it is STILL too long). Enough for us to spend probably 2 hours discussing if you wanted to:

    • He claimed total testosterone was more important than free testosterone. This is false. Total testosterone is the combination of bound and unbound testosterone. 98% of it is bound to SHBG and Albumin (you know this). Take two guys with total T of 800. One has low SHBG and the other has high SHBG. One has a free T of 30 ng/dL and the other has a free T of 8 ng/dL. Same total, but the guy with 30 feels a hell of a lot better than the guy with 8! This is why FREE T is the most important piece here. Total is virtually irrelevant.

    • You can’t just measure TSH for thyroid. At the very least you need Free T3 and Free T4. He made it sound like optimizing thyroid is unnecessary. It is absolutely necessary for many, many guys and oftentimes the reason TRT isn’t working for them in the first place.

    • When you are measuring hematocrit and hemoglobin, you measure platelets as well. Elevated hematocrit and hemoglobin are normal and to be expected on TRT (this is called Erythrocytosis). It’s only when platelets get out of control can it be dangerous (Polycythemia Vera) which is actually a form of cancer. One doesn’t turn into the other. Plenty of athletes use compounds like EPO to raise h/h to have better oxygenation of the blood = better performance. Higher levels of h/h is a non-issue. No need for phlebotomy whatsoever.

    • He said TRT is not a permanent solution. Huh? Let’s get the guy’s T levels optimized, feeling great, all symptoms resolved. Then let’s take him off T with suppressed natural production? Let it take 6 months for his levels to ‘maybe’ come back to healthy levels? This is nuts. TRT is for life. Any clinic that tells a patient that they can do this temporary are lying to their patients.

    • He claims he wants to do ‘responsible TRT’ yet he blocks estrogen? He claimed estrogen is related to inflammation! What!? Please do show the evidence for this in the literature. Roughly half of the benefits you get from TRT is from the conversion to estrogen. Libido, erections, bone mineral density, cognition, cardiovascular health, reduced risk for diabetes and Alzheimer’s, reduced chance of stroke, etc. etc. All from Estrogen! Not to mention, it has a direct impact on muscle growth! He says he doesn’t feel good unless he takes an AI. This is due to a poor protocol and zero understand of the action of estrogen in men. Every single doc I work with doesn’t block estrogen. We’re talking a combined tens of thousands of patients. Not one of them on an AI. He said he measured bone mineral density after a few months with a guy on an AI. You won’t see this after a few months. An AI is a slow poison that destroys endothelial and cardiovascular function, and tons more, over time. Never, ever block E2.

    • He claimed that FSH and LH don’t do down with the cream. This is beyond nonsense. ANY exogenous testosterone will eventually crash natural production.

    • The scrotal application is the undisputed BEST application site (you knew this too and he didn’t). 8 times greater absorption compared to anywhere else (lots of literature on this). Back of the knees? Guess he just wants to sell more cream to his patients because they will need to apply significantly more. He’s worried that scrotal will affect his balls. I couldn’t believe it! It is the scrotal SKIN that is absorbing the cream, not his balls! He also said it converted MORE to estradiol than other application sites which is also false. If anything, we are seeing the cream convert LESS to estradiol compared to injections. Lots of talk about why scrotal is bad meanwhile he has never done it himself and never actually tried it at his practice. Plus you get a boost in DHT due to higher levels of 5-Alpha-Reductase in scrotal skin. Ignorance at its best.

    • 300mg of injections every 3 weeks causes cardiovascular disease? (agreed that it is a stupid protocol) I will give him the keys to my house if he can prove this (he can’t, because it is nonsense). Testosterone has been studied for over 80 years. In every study, no harm was found regardless of the dose or frequency.

    I have no business angle here. I help guys for free. I have a business that has nothing to do with this stuff. Misinformation on this subject angers me because guys learn ‘bro science’ and wind up feeling like crap. I want guys to feel better. It’s my way of giving back from all the guys who helped me.

    You probably already knew half this stuff. I can teach you the other half. Explain it to your viewers in simple English and demonstrate it with logic and common sense. Literature to back up any of it upon request.

  19. Chris B says:

    I was on compounded cream for over a year and my testosterone actually went down from 175 to 66. I have now transitioned to injections and I feel the improvement. You mentioned some patients are resistant to trans dermal treatment. Are there any solutions other than injection?

    1. Danny Bossa says:

      Scrotal cream application which has 8 times greater absorption than anywhere else on the body. Versabase or similar cream, 20% concentration, 200mg/gram, ideally applied twice daily. Your levels most likely tanked due to application elsewhere on the body (shoulders, chest etc)

    2. Reb says:

      Your cream was poorly made

    3. Adam says:

      That’s a great question. Switching to a different cream can be good. Cream strength can vary as well.

  20. Josh says:

    I’ve had the pleasure of working with Adam and wow!! Does he know his stuff when it comes to HRT. Refreshing to see someone who is so helpful in a convoluted market of disinformation around a topic.

    1. adam says:

      Thanks, man! We are here to serve. Hope you like the podcast too.

    2. Jamie says:

      But he doesn’t apparently.
      If Danny Bossa’s comment isn’t deleted (for a 2nd time) by the time you read this, read his comments.
      His observations are truly based in science. Adam is running a business for profit.

      1. Adam says:

        Does Danny Bossa work for a clinic that manages patients hormone therapy?

        1. Danny Bossa says:

          Danny deals with the best phsycians in the world who do and speaks with them daily.

          Get your facts straight. Are you a doctor? No. Stop challenging people’s credentials when you have none of your own.

  21. Johnny G says:

    Would these hormone tests apply to someone who is suffering from male pattern baldness to optimize levels?

    1. Adam says:

      Johnny, we can definitely explore the options of hormone optimization with you if you have the symptoms in line to sub optimal hormone issues. In our Regenerative Medicine clinic in Texas, we do some hair restoration PRP/Amnionic fluid treatments (im doing it Monday for my reseeding hair line).

    2. adam says:

      Johnny, please give us a shout and we can discuss the options that might work best for you!

    3. Reb says:

      Hair loss is genetic. It’s gonna happen or it isn’t.

  22. Phil W says:

    Where can we purchase this cream for fat loss spot reduction?

    1. Adam says:

      Phil,

      We can help with that at the renew life RX clinic.

    2. Danny Bossa says:

      I’ve got a bridge to sell you….

  23. When you say I do blood this test because I trust it and I don’t know how to interpret other test is a sign of laziness. That is like saying the reason I do something is because that is how I have always done it. Blood is not a good measure of fat soluble hormones.

    1. Adam says:

      Dr. Taylor,

      We do blood tests only because of the success we have had with thousands of people. We are not against saliva or urine or others, but it is not part of our current model.

      I would hardly say our constant communication and 86% retention rate of clients is a sign of laziness.

      We would love to hear your detailed solution on how you feel our team could do a better job and also share some successes in with your methods.

      Thanks so much

      1. Eddie R says:

        Adam do you have anything to do with Danny Bossa comments being taken down? Is it because he can prove you wrong with medical literature? How about a debate with you two and Ben moderate?

        1. It was not deleted, but flagged due to length. It's been restored!

    2. Danny Bossa says:

      Absolutely agreed, Eldred. In particular for women’s hormones as serum levels will only provide a single snapshot in time for a 28 day cycle. Serums tests become meaningless here.

      1. Danny Bossa Hypocrisy :

        Insulting Ben of a douchebag in his group and making a post whining about his comment in this blog post being deleted. Sh*t all over Jay Campbell because of his twitter posts not his content when Jay got the best books and youtube channel on TRT hand down. Claim Jay never wrote his books but Jim did without any proofs (I contacted Jim, he said the books were a collaboration) Then delete my comment and block me on facebook when I shoved those facts to his face.

        Too bad, “TRT and Hormone Optimization” might be the best facebook group on TRT.

        Dignam,
        TCity

    3. Jordan Grant says:

      Agree with Dr Taylor. Not only is this because they are fat soluble, but also because of what we now know about intracrinology and hormones.

      Most of the hormones we need (mainly the metabolites of T –> DHT and e2) are made intracellularly. The serum levels are a mere poor reflection of total tissue ACTION.

      This is a HUGE confounder for all studies relying on serum levels, especially of metabolites, but I’d say even of testosterone itself.

      Danny Bossa and I are going to be discussing how this relates to estradiol in a video soon.

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